Clearly from Greek
lyssa: madness, rage
(1) +
manes. (Greek
manes is a cup, or slave
(2), but unclear if this is the correct root in this context.)
Most sources (such as
The Free Dictionary) note that
lysso- specifically refers to rabies, "canine madness".
Wiktionary notes suffix
-mane is from Ancient Greek
-manḗs, apparently meaning a mad person. So perhaps
Lyssomanes refers to the energetic, seemingly crazy, movements of this spider.