Abstract: This taxonomic review of the Cuban Miridae (Hemiptera: Heteroptera) treats 105 species in 57 genera. Twelve new species are described, two new synonyms are recognized, and four previously recorded species are removed from the list. All genera and species are diagnosed, and a thorough literature review and information on host plants and distribution are given. Male genitalia are illustrated and a color image is provided for nearly all species. Identification keys to subfamilies, tribes, genera, and species are included, and the biogeography of the Cuban and West Indian mirid fauna is discussed. This work will form a solid foundation for future research on the plant bugs of Cuba, providing a summary of the information known about each species and the means to accurately identify them.